- Feb 12 Thomas Campion, English composer, poet and physician, born in London, England (d. 1620)
- Apr 25 Aurelio Signoretti, Italian composer, born in Reggio Emilia, Italy (d. 1635)
- Apr 26 Nicolas Formé, French composer, born in Paris (d. 1638)
- May 15 Claudio Monteverdi, Italian composer and pioneer in development of opera (L'Orfeo, espro della Beata Vergine), baptized in Cremona, Italy (d. 1643)
- Aug 10 Girolamo Giacobbi, Italian singer, choirmaster, conductor, and composer of sacred music and opera, baptized in Bologna, Papal States (now Italy) (d. 1629)
- Dec 15 Christoph Demantius, German composer, born in Reichenberg , Duchy of Bavaria (d. 1643)
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