- May 3 Nicola De Giosa, Italian composer, born in Bari, Kingdom of the Two Sicilies (d. 1885)
- May 5 Stanisław Moniuszko, Polish conductor, composer (Straszny dwór - The Haunted Manor), and teacher, born in Ubiel, Minsk Governate, Russian Empire (now Belarus) (d. 1872)
- May 17 Johann Nepomuk Kafka, Bohemian pianist and composer, born in Neustadt an der Mettau (d. 1886)
- May 18 Julius Hopp, Austrian composer, born in Vienna (d. 1885)
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