- Apr 1 Trinh Công Son, Vietnamese poet and songwriter, dies at 64
- Apr 3 Lester "Big Daddy" Kinsey, American Chicago blues singer, guitarist and harmonica player, dies at 74
- Apr 6 Charles Pettigrew, American soul singer (Charles & Eddie - "Would I Lie To You?"), dies of cancer at 37
- Apr 9 Graziella Sciutti, Italian operatic soprano, teacher, and opera producer, dies at 64 [1]
- Apr 11 Harry Secombe, Welsh actor, comedian, singer and goon (The Goon Show; Oliver!), dies of cancer at 79
- Apr 11 Sandy Bull, American musician (b. 1941)
- Apr 12 Alberto Erede, Italian conductor, dies at 91
- Apr 15 Joey Ramone [Jeffrey Hyman], American punk rock singer and musician (The Ramones - "I Wanna Be Sedated"; Blitzkrieg Bop"; solo -"What a Wonderful World"), dies of lymphoma at 49
- Apr 15 John Verrall, American composer, dies at 92
- Apr 20 Giuseppe Sinopoli, Italian conductor and composer (Sunnyata; Lou Salomé), dies while conducting Verdi's "Aida" of a heart attack at 54
- Apr 20 Maria Karnilova, American dancer and actress (Fiddler on the Roof, Ivan the Terrible), dies at 80
- Apr 21 David Hollestelle, Dutch baritone singer (Dutch Radio Chorus), dies at 84
- Apr 22 Ludvig Nielsen, Norwegian organist, composer, choir director, and conductor (Nidaros Cathedral, 1935-76), dies at 95
- Apr 24 Al Hibbler, American singer ("Unchained Melody"), dies at 85
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