- Oct 5 Steve Lee [Stefan Alois], Swiss rock musician and vocalist (Gotthard), dies in a vehicle crash at 47
- Oct 6 Antonie Kamerling, Dutch actor and singer (b. 1966)
- Oct 6 Colette Renard, French actress and singer (b. 1924)
- Oct 7 (Terry) "T" Lavitz, American jazz-fusion keyboardist (Dixie Dregs; Jazz Is Dead), dies at 54
- Oct 10 Dame Joan Sutherland, Australian operatic soprano, known as 'La Stupenda' (Metropolitan Opera debut 1961), dies at 83
- Oct 10 Solomon Burke [McDonald], American soul singer ("Cry To Me"; "Diamond In Your Mind"), dies at 70
- Oct 13 General Johnson, American soul singer and songwriter (Chairmen of the Board - "Give Me Just a Little More Time"), and songwriter ("Patches"; "Want Ads"), dies of lung cancer at 69
- Oct 16 Eyedea [Micheal Larsen], American poet and rapper (Eyedea & Abilities), dies from opiate induced respiratory depression at 28
- Oct 18 Marion Brown, American jazz alto saxophonist, (Marion Brown Quartet; John Coltrane -"Ascension"; Artie Schepp), avant garde composer, writer, and ethnomusicologist, dies at 79
- Oct 20 Harvey Phillips, American tubist (NYC Ballet Orchestra), dies at 80
- Oct 25 Gregory Isaacs, Jamaican reggae musician, dies of lung cancer at 59
- Oct 26 John King, American rock drummer (Steve Miller Band, 1972-74), dies at 63
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