- Apr 1 C. W. McCall [William Dale Fries, Jr.], American country singer (Convoy), dies of cancer at 93
- Apr 1 Roland White [LeBlanc], American bluegrass mandolin player and vocalist (Kentucky Colonels; Lester Flatt's Nashville Grass), dies after a heart attack at 83
- Apr 4 Joe Messina, American soul, jazz, and R&B session guitarist (Soupy Sales; The Funk Brothers), dies at 93 [1]
- Apr 5 Bobby Rydell [Ridarelli], American pop singer ("Wild One"; "Wildwood Days"), and actor (Bye Bye Birdie), dies of pneumonia at 79 [1]
- Apr 5 Boris Brott, Canadian conductor (Hamilton Philharmonic, 1969-90) and music promoter (Brott Music Festival: National Academy Orchestra of Canada), killed in a hit-and-run accident at 78
- Apr 5 Paul Siebel, American folk singer and songwriter (Louise; Spanish Johnny), dies from complications of pulmonary fibrosis at 84
- Apr 13 Gloria Parker [Rosenthal], American marimbist, glasspiel player, songwriter (Clap Your Hands and Shake Your Blues Away), and bandleader, dies at 100 [1]
- Apr 15 Art Rupe [Goldberg], American gospel, R&B, and early rock record producer and label executive (Specialty Records - Little Richard, Sam Cooke, Lloyd Price), dies at 104
- Apr 17 Radu Lupu, Romanian Grammy Award-winning concert pianist (Van Cliburn Competition - gold, 1966; George Enesco Competition - 1st prize, 1967), dies at 76
- Apr 17 Re Styles [Shirley Macleod], Dutch-American actress (Space Is The Place), designer, and rock vocalist (The Tubes, 1976-79), dies at 72
- Apr 18 Harrison Birtwistle, British contemporary classical composer (The Minotaur; The Mask of Orpheus), dies at 87 [1]
- Apr 18 Janez Matičič, Slovenian pianist. conductor, and pedagogue, dies at 95
- Apr 18 Nicholas Angelich, American concert pianist, dies of degenerative lung disease at 51
- Apr 20 Guitar Shorty [David William Kearney], American blues-rock guitarist, singer and songwriter (You Don't Treat Me Right), dies at 87
- Apr 20 Robert Morse, American Tony and Emmy Award-winning stage and screen singer and actor (Mad Men; How to Succeed in Business Without Really Trying), dies at 90 [1]
- Apr 23 Arno [Arnold Hintjens], Belgian rock singer-songwriter (TC Matic), pancreatic cancer at 72
- Apr 24 (Wilhelm) "Willi" Resetarits, Austrian singer and human rights activist, dies at 73
- Apr 27 Judy Henske, American folk singer (High Flying Bird), dies at 85
- Apr 30 (Diana) "Naomi" Judd, American Grammy Award-winning country singer (The Judds - "Why Not Me"), dies of a self-inflicted gunshot at 76
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