Major Events
- Feb 18 Hernán Cortés leaves Cuba for the Yucatan Peninsula, Mexico with 11 ships and 500 men
- Jun 28 King Carlos I elected Holy Roman Emperor Charles V
- Jul 16 Public debate between Martin Luther and theologian Johann Eck at Pleissenburg Castle in Liepzig, during which Luther denies the divine right of the Pope
- Jul 26 Francisco Pizarro receives royal charter for the west coast of South America
- Sep 20 Spanish expedition led by Portuguese navigator Ferdinand Magellan sets off on the 1st successful circumnavigation of the globe (Magellan killed on route)
- Nov 8 1st meeting of Aztec Emperor Moctezuma II and Spanish Conquistador Hernán Cortés in Tenochtitlan, Mexico
- More 1519 Events